Battle of Gaugamela (331 BC): The Fall of the Persian Empire
Decisive Macedonian victory; Darius III fled and the Achaemenid Persian Empire collapsed, leaving Alexander master of its heartland.
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Decisive Macedonian victory; Darius III fled and the Achaemenid Persian Empire collapsed, leaving Alexander master of its heartland.
The main palaces of Persepolis were destroyed by fire after their treasury had been looted, and the city never regained its royal role.
Alexander died without an adult heir; his generals divided the empire and soon went to war, leading to its break-up into rival kingdoms.
After losing its eastern provinces to Parthia and its western lands to Rome, the Seleucid kingdom was reduced to Syria and annexed by Pompey as a Roman province.
Petra grew into the wealthy capital of the Nabataean kingdom, became part of the Roman province of Arabia in AD 106 and is now Jordan's best-known World Heritage Site.
Three Celtic tribes settled central Anatolia, raided their neighbours for decades and eventually became the Roman province of Galatia in 25 BC.
Nisa became one of the earliest royal centres of the Parthian Empire, and its excavated fortress is a key source for Parthian art, language and administration.
The scrolls became the oldest known manuscripts of the Hebrew Bible and a unique window on Judaism in the Second Temple period.
The Parni under Arsaces took Parthia and Hyrcania from Seleucid control and founded the Arsacid dynasty, which ruled Iran until AD 224.
Ptolemaic victory; Egypt kept Coele-Syria and the Fourth Syrian War ended.
The rebels restored Jewish worship in the Temple and won religious freedom; within two decades the Hasmonean family ruled an independent Judea.
Tigranes created the largest Armenian state in history, but after defeats by Lucullus he submitted to Pompey in 66 BC and kept only Armenia as a Roman ally.